John 8:21

But of His own passion itself, which lay not in any necessity He was under, but in His own power, all that He said in His discourse to the Jews was, "I go away." For to Christ the Lord's death was His proceeding to the place whence He had come, and from which He had never departed. "I go away," said He, "and ye shall seek me," not from any longing for me, but in hatred. For after His removal from human sight, He was sought for both by those who hated Him and those who loved Him; by the former in a spirit of persecution, by the latter with the desire of having Him. In the Psalms the Lord Himself says by the prophet, "A place of refuge hath failed me, and there is none that seeketh after my life;" and again He says in another place in the Psalms, "Let them be confounded and ashamed who seek after my life." He blamed the former for not seeking, He condemned the latter because they did. For it is wrong not to seek the life of Christ, that is, in the way the disciples sought it; and it is wrong to seek the life of Christ, that is, in the way the Jews sought it: for the former sought to possess it, these latter to destroy it. Accordingly, because these men sought it thus in a wrong way, with a perverted heart, what next did He add? "Ye shall seek me, and"-not to let you suppose that ye will seek me for good-"ye shall die in your sin." This comes of seeking Christ wrongly, to die in one's sin; this of hating Him, through whom alone salvation could be found. For, while men whose hope is in God ought not to render evil even for evil, these men were rendering evil for good. The Lord therefore announced to them beforehand, and in His foreknowledge uttered the sentence, that they should die in their sin.

And then He adds, "Whither I go, ye cannot come." He said the same to the disciples also in another place; and yet He said not to them, "Ye shall die in your sin." But what did He say? The same as to these men: "Whither I go, ye cannot come." He did not take away hope, but foretold delay. For at the time when the Lord spake this to the disciples, they were not able to come whither He was going, yet were they to come afterwards; but these men never, to whom in His foreknowledge He said, "Ye shall die in your sin."

(Tract. xxxviii. 2) In accordance with what was just, He said that no man laid hands on Him, because His hour was not yet come; He now speaks to the Jews of His passion, as a free, and not a compulsory sacrifice on His part: Then said Jesus again unto them, I go My way. Death to our Lord was a return to the place whence He had come. (Tract. xxxviii. 2) Ye shall seek Me, then, He says, not from compassionate regret, but from hatred: for after He had departed from the eyes of men, He was sought for both by those who hated, and those who loved Him: the one wanting to persecute, the other to have His presence. And that ye may not think that ye shall seek Me in a good sense, I tell you, Ye shall die in your sin. (ἁμαρτίᾳ plural in our Transl.) This is to seek Christ amiss, to die in one's sin: this is to hate Him, from Whom alone cometh salvation. He pronounces sentence on them prophetically, that they shall die in their sins. (Tract. xxviii. s. 2) This He tells His disciples in another place; without saying to them, however, Ye shall die in your sin, He only says, Whither I go, ye cannot follow Me now; not preventing, but only delaying their coming.

and whither I go, YE cannot come. Not only does He say that they shall die in their sins, but declares clearly that, ascending not to the mansions above, they will remain outside of the good things of the kingdom: for they who received not Him Who came from above, how could they also follow Him ascending up? Double therefore is the punishment to them who believe not, and not in any single thing their loss. For just as they who have fallen into bodily loss of health must needs suffer and endure the trials of the suffering and besides be deprived of the pleasures of health; so and not otherwise do they who have departed into Hades, and there undergo punishment proportionate to the sins, both endure the state of punishment and lose the enjoyment of the hope of the saints. Most excellently then does our Lord Jesus Christ say not only that they shall die in their sins, but also that they shall not mount up to the mansions above: for binding them as by a twofold cord, does He haste to draw them away from their inherent ill-counsel. From all sides saving that which was lost and binding up the broken and raising up that which was broken down (for these are the ways of a Good Shepherd and One Who readily gives His Life for the salvation of the sheep) does He tell His own disciples, I will go and prepare a place for you, and will come again and receive you with Myself, showing that the very heaven will be accessible to the saints and teaching that the mansions above have been prepared for them that love Him, but to those who have chosen to disbelieve Him, rightly and needs does He say, Whither I go YE cannot come. For who at all will follow the All-holy Christ, if he love not the cleansing that is through faith? or how shall he that is yet defiled and that has not cleared off the filth from his passions be with our Lord Who loves us? […]

He said therefore unto them again, I go My way, and ye shall seek Me and shall die in your sins. That we must needs take hold of the present time for whatever one may receive profit from to oneself, does Christ herein well declare unto us. For to be too late in what is good and to take after-counsel for what is profitable, clearly brings no gain but ministers wailing befitting the neglect. Our Lord therefore being good and gracious, as it is written, both bears with those who dishonour Him and aids those who insult Him and is found as God superior to all the littleness of man. Yet does He for their good threaten to depart from them, and says plainly I go My way, that He may implant in them a more resolved mind, and that they considering that they ought not to leave their Redeemer when present frustrate of His work, He may whet them to pass on to the faith and may make them now at length more ready unto obedience. And having cried out, I go My way, and threatened departure from the whole nation, He subjoined economically the damage therefrom ensuing unto them. For (He says) Ye shall die in your sins; and we shall see the nature of the thing bringing in the truth of what is said. For they who did not at all receive Him Who came to us from Heaven that He might justify all through faith, how shall they not beyond all contradiction die in their sins, and not receiving Him Who can cleanse them, how will they not have lasting defilement from their impiety? For to die unredeemed, yet laden with the weight of sin, to whom is it any doubt where this will conduct the soul of man? […]