Genesis 12:2

The scope of the promise is extraordinary: "I will make you a great nation; I will bless you and magnify your name." Not only will I place you at the head of a great nation and cause your name to be great, but as well, "I will bless you, and you will be blessed." I will favor you with so much blessing, he says, that it will last for all time. "You will be blessed" to such an extent that everyone will be anxious to thrust themselves into your company in preference to the highest honor. See how God right from the beginning foretold to him the honor he would later confer upon him. "I will make you a great nation," he said; "I will magnify your name; I will bless you, and you will be blessed." Hence the Jews too found in the patriarch grounds for self-importance and endeavored to establish their kinship with him in the words "We are the children of Abraham." For you to learn, however, that on the basis of their evil ways they are in fact unworthy of such kinship, Christ says to them, "If you were children of Abraham, you would do the works of Abraham." John too, the son of Zechariah, when those anxious to be baptized flocked to the Jordan, said to them, "Brood of vipers, who warned you to flee from the wrath to come? Bear fruit that benefits repentance, and don't presume to say, 'We have Abraham for our father.' I tell you, after all, that God can raise up children to Abraham even from these stones." Do you see how great his name was in everyone's estimation? For the time being, however, before the sequel the just man's God-fearing qualities are demonstrated in the way he believed the words coming from God and accepted without demur everything, difficult though it seemed.

Abraham, styled "the friend," [Isaiah 41:8] was found faithful, inasmuch as he rendered obedience to the words of God. He, in the exercise of obedience, went out from his own country, and from his kindred, and from his father's house, in order that, by forsaking a small territory, and a weak family, and an insignificant house, he might inherit the promises of God. For God said to him, "Get you out from your country, and from your kindred, and from your father's house, into the land which I shall show you. And I will make you a great nation, and will bless you, and make your name great, and you shall be blessed. And I will bless them that bless you, and curse them that curse you; and in you shall all the families of the earth be blessed." [Genesis 12:1-3] And again, on his departing from Lot, God said to him, "Lift up your eyes, and look from the place where you now are, northward, and southward, and eastward, and westward; for all the land which you see, to you will I give it, and to your seed forever. And I will make your seed as the dust of the earth, [so that] if a man can number the dust of the earth, then shall your seed also be numbered." [Genesis 13:14-16] And again [the Scripture] says, "God brought forth Abram, and spoke unto him, Look up now to heaven, and count the stars if you are able to number them; so shall your seed be. And Abram believed God, and it was counted to him for righteousness." [Genesis 15:5-6] On account of his faith and hospitality, a son was given him in his old age; and in the exercise of obedience, he offered him as a sacrifice to God on one of the mountains which He showed him.

And the Lord said to Abram, "Go out from your land, and from your kindred, and from your father's house to the land that I will show you.

And I will make of thee a great nation,....

I will make of thee a great nation - i.e., The Jewish people; and make thy name great, alluding to the change of his name from Abram, a high father, to Abraham, the father of a multitude.