Romans 1:4

It must be observed that he does not say: Who was predestined the Son of God in power according to the Spirit of sanctification; but, Who was destined the Son of God. And let no one think that we are examining this expression more curiously than the matter allows. For although in the Latin copies "predestined" is customarily found, nevertheless according to what the truth of the interpretation holds, "destined" is written, not "predestined." For he who is is destined, but he who is not yet is predestined, as are those of whom the Apostle says: "But whom he foreknew, them he also predestined." Therefore those who are not yet can be foreknown and predestined; but he who is, and always is, is not predestined, but destined. Let these things be said by us on account of those who speak impiety against the only-begotten Son of God, and, being ignorant of the difference between "destined" and "predestined," suppose that he is to be numbered among those who, since they did not exist before, were predestined that they should exist — he who was never predestined to be the Son, but always was and is, just as the Father also is. He therefore who always is, is destined, as we have said, not predestined; but he who is predestined was not yet at the time when he was being predestined, but began from time. The Apostle therefore uses a necessary distinction, saying that he who is from the seed of David according to the flesh was made; but him whom he names the Son of God in power according to the Spirit of sanctification, destined. And indeed, when he had said "Son of God," he added not superfluously, "in power," indicating by this that he is Son in substance according to the Spirit of sanctification. […]

In what way indeed he who is said according to the flesh to have been made of the seed of David is Son of God from the resurrection of the dead, it is not difficult to perceive for one who has read that which is written: "For it was fitting that he through whom are all things, and in whom are all things, in bringing many sons unto glory, should perfect the author of their salvation through sufferings." Now the end of Christ's sufferings is the resurrection; and because after the resurrection he dies no more, "death shall no longer have dominion over him"; and again it is said that, "even if we have known Christ according to the flesh, yet now we know him so no longer", and therefore all that is in Christ is now already Son of God. But in what way this too is to be referred to him who "was destined Son of God in power" — this constrains our understanding, save that through the indissoluble unity of the Word and the flesh all things that belong to the flesh are ascribed also to the Word, just as the things that belong to the Word are also predicated of the flesh. But "Jesus" and "Christ" and "Lord" we find often referred to both natures alike, as in that passage: "One Lord of ours, Jesus Christ, through whom are all things"; and: "For if they had known, they would never have crucified the Lord of majesty." Christ, then, is called the first-fruits, or the firstborn, from the dead. […]

Before his crucifixion and death the Lord Jesus Christ did not appear to be God either to the Jews or even to the disciples. For they were offended by human things, as when they saw him eating and drinking and sleeping and urinating, and not …

"And declared to be the Son of God with power, according to the Spirit of Holiness, by the resurrection from the dead, even Jesus Christ." What is said has been made obscure by the close-folding of the words, and so it is necessary to divide it. What then is it, which he says? We preach, says he, Him Who was made of David. But this is plain. Whence then is it plain, that this incarnate "Person" was also the Son of God? First, it is so from the prophets; wherefore he says, "Which He had promised afore by the Prophets in the Holy Scriptures." And this way of demonstration is no weak one. And next also from the very way of His Generation: which also he sets forth by saying, "of the seed of David according to the flesh": for He broke the rule of nature. Thirdly, from the miracles which He did, yielding a demonstration of much power, for "in power" means this. Fourthly, from the Spirit which He gave to them that believe upon Him, and through which He made them all holy, wherefore he saith, "according to the Spirit of holiness." For it was of God only to grant such gifts. Fifthly, from the Resurrection; for He first and He alone raised Himself: and this Himself too said to be above all a miracle sufficient to stop the mouths even of them that behaved shamelessly. […]

Above he said: "concerning His Son," and now he proves how He was known as the Son of God, and says that He was declared, that is, shown, established, recognized; for declaration is recognition itself, a verdict and decision. For all recognized and decided that …

By his miracles and resurrection and by the descent of the Holy Spirit, it was made plain and certain to the world that Christ was the Son of God.

Having commended Christ's origin, he now commends his power, and mentions three things. First, his predestination, when he says, who was predestined; second, his dignity or power, when he says, the Son of God in power; third, the sign or effect, when he says, according …

But powerfully declared to be the Son of God, according to the Spirit of Holiness - That is, according to his divine nature. By the resurrection from the dead - For this is both the fountain and the object of our faith; and the preaching of the apostles was the consequence of Christ's resurrection.

4 ), he is the Son of God. The great proof or demonstration of this is his resurrection from the dead, which proved it effectually and undeniably. The sign of the prophet Jonas, Christ's resurrection, was intended for the last conviction, Matt. xii.

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And declared to be the Son of God,....

Observe, When Paul mentions Christ, how he heaps up his names and titles, his Son Jesus Christ our Lord, as one that took a pleasure in speaking of him; and, having mentioned him, he cannot go on in his discourse without some expression of love and honour, as here, where in one person he shows us his two distinct natures.

And declared to be the Son of God - See the note on Act 13:33, where this subject is considered at large. The word ορισθεντος, which we render declared, comes from οριζω, to bound, define, determine, or limit, and hence our word horizon, the line that determines the farthest visible part of the earth, in reference to the heavens. In this place the word signifies such a manifest and complete exhibition of the subject as to render it indubitable.

This is here styled the "spirit," as an impalpable and immaterial nature (Joh 4:24), and "the spirit of holiness," probably in absolute contrast with that "likeness, of sinful flesh" which He assumed. One is apt to wonder that if this be the meaning, it was not expressed more simply.

And declared - In the margin, “determined.” Τοῦ ὁρισθέντος Tou horisthentos. The ancient Syriac has, “And he was known to be the Son of God by might and by the Holy Spirit, who rose from the house of the dead.” The Latin Vulgate, “Who was “predestinated” the Son of God,” etc. The Arabic, “The Son of God destined by power special to the Holy Spirit,” etc. The word translated “declared to be” means properly “to bound, to fix limits to,” as to a field, to determine its proper limits or boundaries, to “define,” etc. Act 17:26, “and hath determined the bounds of their habitation.” Hence, it means to determine, constitute; ordain, decree; i, e. to fix or designate the proper boundaries of a truth, or a doctrine; to distinguish its lines and marks from error; or to show, or declare a thing to be so by any action. Luk 22:22, “the Son of man goeth as it was determined, as it was fixed; purposed, defined, in the purpose of God, and declared in the prophets. Act 2:23, “him being delivered by the determinate counsel, the definite. constituted will, or design, of God. Act 11:29; Heb 4:7, “he limiteth a certain day,” fixes it, defines it. In this sense it is clearly used in this place. The act of raising him from the dead designated him, or constituted him the Son of God. […]