Psalms 38:21

"Forsake me not, O Lord; O my God, depart not from me" [Psalm 38:21]. Let us speak in Him, let us speak through Him (for He Himself intercedes for us), and let us say, "Forsake me not, O Lord my God." And yet He had said, "My God! My God! Why have You forsaken Me?" [Matthew 27:46] and He now says, "O My God, depart not from Me." If He does not forsake the body, did He forsake the Head? Whose words then are these but the First Man's? To show then that He carried about Him a true body of flesh derived from him, He says, "My God, My God why have You forsaken Me?" God had not forsaken Him. If He does not forsake You, who believest in Him, could the Father, the Son, and the Holy Ghost, One God, forsake Christ? But He had transferred to Himself the person of the First Man. We know by the words of an Apostle, that "our old man is crucified with Him." [Romans 6:6] We should not, however, be divested of our old nature, had He not been crucified "in weakness." For it was to this end that He came that we may be renewed in Him, because it is by aspiration after Him, and by following the example of His suffering, that we are renewed. Therefore that was the cry of infirmity; that cry, I mean, in which it was said, "Why have You forsaken Me?" Thence was it said in that passage above, "the words of mine offenses." As if He were saying, These words are transferred to My Person from that of the sinner.

Lord, you heal and are not polluted; you help and are not contaminated; for you are a God who saves. Your hands, O Lord, do not lose those that are your own but heal them.

"Do not forsake me, O Lord." Here is set forth the prayer; and he asks that what he fears be removed, and he asks that what he loves be given to him, at "Attend to my help." Here he asks that what he fears not …

Forsake me not, O Lord,.... Or continue not to forsake; for he seems to have been under divine desertion, and might be under apprehensions that God had utterly forsaken him; which he entreats he would not, though his friends had forsook him, and his own strength had failed and left him, Psa 38:10; O my God, be not far from me; as to his gracious presence, and with respect to help and deliverance, otherwise God is not far from any of his creatures, being omnipresent.

He pleads, "Thou art my God, whom I serve, and on whom I depend to bear me out; and my salvation, who alone art able to save me, who hast engaged thyself by promise to save me, and from whom alone I expect salvation." Is any afflicted? let him thus pray, let him thus plead, let him thus hope, in singing this psalm.