Zechariah 12:1

I do not want anyone to tell me that this view [that God condemns innocent souls] should be supported by the passage "who formed the spirit of man in him" and "who made the heart of every one of them." Something supremely strong and invincible is needed to force me to believe that God condemns any souls without any guilt of theirs. It is either as great a thing, or it is, perhaps greater, to create as to form, yet it is written, "Create a clean heart in me, O God." This is no argument for thinking that the soul in this passage prays to be made before it had any being. As, therefore, while now existing, it is created by renewal of its justice, so, while now existing, it is formed by the shaping force of doctrine.

Hence we ought to understand this passage so that we do not take the words "he breathed into him the breath of life, and he became a living soul" to mean that a part, as it were, of the nature of God was turned into the soul of man. Thus we are not forced to say that the nature of God is mutable. It is especially in this error that the truth weighs down upon these Manichaeans. For as pride is the mother of all the heretics, they dared to say that the soul is the nature of God. And thus they are under pressure from us when we say to them, "Then the nature of God errs and is unhappy and is corrupted by the stain of vices and sins, or is, as you say, soiled by the filth of the opposing nature," and other such things that it is wicked to believe about the nature of God. For in another passage Scripture clearly says that the soul was made by almighty God and that it is therefore not a part of God or the nature of God. There the prophet says, "He who formed the spirit for all men made all things," and in another place it says, "He who formed the spirit of man is in him." These testimonies clearly prove that the spirit of man was made. In Scripture the rational part of man's soul by which he differs from the beasts and rules over them by the law of nature is called the spirit of man. On this the apostle says, "No one knows what pertains to man except the spirit of man which is within him." If these testimonies were not clear proof that the soul of man was made, there would be no lack of those who would say that the spirit of man was not made and who would think that it is the nature of God and say that part of God was changed into it, when there took place that breathing forth by God. […]

There are many statements of spirit in general in the sacred Scriptures, and a person could easily become confused from ignorance, if he did not know to what sort of spirit the particular text refers; therefore we must be sure of the nature of the Holy Spirit according to Scripture. For example, Aaron is called Christ (anointed), and David also, and Saul and others are called christs, yet there is only one true Christ; similarly, since the name of spirit has been given to many things, we must determine what in particular is called the Holy Spirit. Many things are called spirits; our soul is called spirit; this wind, which is blowing, is called spirit; great valor is called spirit; impure action is called spirit; and a hostile devil is called spirit. Take care, therefore, when you hear such things, not to mistake one for another because of the similarity of the name. Scripture says of the soul, "When his spirit departs, he returns to the earth"; and again of the soul: "Who forms the spirit of man within him."

Therefore he referred the thunders to the words of the Lord, the sound of which went out into all the earth. And we understand the word spirit in this place of the soul, which he took endowed with potential reason and perfection. For the Scripture often designates the soul of humankind by the word spirit, as you read: "Who creates the spirit of man within him." So too the Lord signified his soul by the word spirit, when he said, "Into your hands I commend my spirit."

(Chapter 12, Verse 1) The burden of the word of the Lord over Israel: says the Lord, who stretches out the heavens, and lays the foundation of the earth, and forms the spirit of man within him: Behold, I will make Jerusalem a cup of trembling unto all the people round about, and Judah shall be in siege against Jerusalem. And in that day will I make Jerusalem a burdensome stone for all people: all that burden themselves with it shall be cut in pieces, though all the people of the earth be gathered together against it.