Revelation 17:6

And I saw the woman drunk with the blood of the saints, etc. It is one body, opposing within and without: although it seems separated by place, it nevertheless operates in common by the unity of the spirit. Thus, the descendants of the wicked are …

And I saw the woman drunk with the blood of the saints - So that Rome may well be called, "The slaughter-house of the martyrs." She hath shed much Christian blood in every age; but at length she is even drunk with it, at the time to which this vision refers.

And I saw the woman drunken with the blood of the saints,....

"Corruptio optimi pessima"; when the Church falls, she sinks lower than the godless world, in proportion as her right place is higher than the world. It is striking that in Re 17:3, "woman" has not the article, "the woman," as if she had been before mentioned: for though identical in one sense with the woman, Re 12:1-6, in another sense she is not.

And I saw the woman drunken with the blood of the saints, and with the blood of the martyrs of Jesus: and when I saw her, I wondered with great admiration - How exactly the cruelties exercised by the Latin Church against all it has denominated heretics correspond with this description, the reader need not be informed.

And I saw the woman drunken with the blood of the saints - A reeling, intoxicated harlot, for that is the image which is kept up all along. In regard to the phrase “drunken with blood,” compare Jer 46:10. “The phraseology is derived from the barbarous custom (still extant among many pagan nations) of drinking the blood of the enemies slain in the way of revenge. The effect of drinking blood is said to be to exasperate, and to intoxicate with passion and a desire of revenge” (Prof. Stuart, in loco). The meaning here is, that the persecuting power referred to had shed the blood of the saints; and that, in its fury, it had, as it were, drunk the blood of the slain, and had become, by drinking that blood, intoxicated and infuriated. No one need say how applicable this has been to the papacy. Compare, however, the Dan 7:21, Dan 7:25 notes; Rev 12:13-14; Rev 13:15 notes. And with the blood of the martyrs of Jesus - Especially with their blood. The meaning is, that the warfare, in which so much blood was shed, was directed against the saints as such, and that, in fact, it terminated particularly on those who, amidst cruel sufferings, were faithful witnesses for the Lord Jesus, and deserved to be called, by way of eminence, “martyrs.” Compare the notes on Rev 2:13; Rev 6:9; Rev 11:5, Rev 11:7. How applicable this is to the papacy, let the blood shed in the valleys of Piedmont; the blood shed in the Low Countries by the Duke of Alva; the blood shed on Bartholomew’s day; and the blood shed in the Inquisition, testify. And when I saw her, I wondered with great admiration - I was astonished at her appearance, at her apparel, and at the things which were so significantly symbolized by her.