Revelation 13:2

And the dragon gave him his power. Thus the Apostle, speaking of the body of the devil, says: His coming is according to the working of Satan with all power, signs, and lying wonders, and with all deceivableness of unrighteousness in them that perish (2 …

And the beast I saw was like a leopard, etc. It is compared to a leopard because of the diversity of nations; to a bear, because of its malice and ferocity; to a lion, because of its physical strength and the arrogance of its tongue. …

And the beast which I saw was like unto a leopard,....

Thus it represents comprehensively in one figure the world power (which in Daniel is represented by four) of all times and places, not merely of one period and one locality, viewed as opposed to God; just as the woman is the Church of all ages.

And the beast which I saw was like unto a leopard - For a description of the leopard, see the notes on Dan 7:6. It is distinguished for bloodthirstiness and cruelty, and thus becomes an emblem of a fierce, tyrannical power. In its general character it resembles a lion and the lion and the leopard are often referred to together. In this description, it is observable that John has combined in one animal or monster, all those which Daniel brought successively on the scene of action as representing different empires. Thus in Dan 7:2-7 the lion is introduced as the symbol of the Babylonian power; the bear, as the symbol of the Medo-Persian; the leopard, as the symbol of the Macedonian; and a nondescript animal, fierce, cruel, and mighty, with two horns as the symbol of the Roman. See the notes on that passage. In John there is one animal representing the Roman power, as if it were made up of all these: a leopard with the feet of a bear, and the mouth of a lion, with two horns, and with the general description of a fierce monster. There was an obvious propriety in this, in speaking of the Roman power, for it was, in fact, made up of the empires represented by the other symbols in Daniel, and “combined in itself all the elements of the terrible and the oppressive, which had existed in the aggregate in the other great empires that preceded it.” At the same time there was an obvious propriety in the symbol itself; for the bloodthirstiness and cruelty of the leopard would well represent the ferocity and cruelty of the Roman power, especially as John saw it here as the great antagonistic power of the true church, sustaining the papal claim, and thirsting for blood. And his feet were as the feet of a bear - See the notes on Dan 7:5. The idea here seems to be that of strength, as the strength of the bear resides much in its feet and claws. […]